NTEGRA platform: NTEGRA Vita

General information Key features Specification Applications Optional features Configurations

NTEGRA Vita combines the strengths of the excellent SPM with perfect optical microscope for biological and medical applications.

From molecules to living organisms, NTEGRA Vita opens the window to the world of biology and biochemistry. Especially designed to integrate seamlessly with your optical microscope, NTEGRA Vita preserves the in situ environment so that you can observe, image and measure what is really there.

For conventional AFM biological imaging as well as biochemistry and bioorganic applications, NTEGRA Vita uses a unique sealed fluid cell which maintains an enclosed volume. Input/output pipes provide controlled flow of nutrient liquids and a heating element precisely maintains temperature, from room temperature to 60 °C, with an accuracy of ±0.005 °C (typically).

Need the ultimate in resolution? You need “scanning-by-sample”, a mode in which a small sample is scanned with great precision under a fixed probe. Our engineers have developed a special little fluid cell specifically for this application. This cell is also helpful when using expensive chemicals.

From large format to ultrahigh resolution, NTEGRA Vita has a solution for your lab.
Measurements and analysis of probe-to-sample forces in pico- and nano- Newton range provide new insight into cellular properties. “Pushing” a cell with the probe then evaluating the cantilever deflection provides quantitative information about the cell turgidity, cytoskeleton network rigidity, and cellular matrix density. “Touching” the surface-bound receptor molecules with a ligand-coated probe quantifies molecular interaction forces. NTEGRA Vita low noise closed loop sensors afford unprecedented accuracy of both probe movement and force measurements.